HelmholtzZentrum munich

Connecting genetic risk to disease endpoints through the human blood plasma proteome


Proteome annotation
Locus annotations

Locus 284

Top associations per target

Target cis/​trans Study SNP SNP location Maj/​min allele MAF N βinv seinv Pinv fclog Plog Praw
LAG-1 cis Discovery rs3213636 17:34,475,131 C/A 0.19 994 -0.454 0.057 6.1×10-15 -1.120 3.1×10-9 0.002


Regional association plots


Boxplots and histograms for top associations

C-C motif chemokine 4-like (LAG-1)

inverse-normalized probe levels log2 transformed probe levels raw probe levels
Discovery study

C-C motif chemokine 4-like (LAG-1)

Target (abbrv.) LAG-1
Target (full name) C-C motif chemokine 4-like
Somalogic ID (Sequence ID) SL004356 (2781-63_2)
Entrez Gene Symbol CCL4L1
UniProt ID Q8NHW4
UniProt Comment
  • Chemokine that induces chemotaxis of cells expressing CCR5 or CCR1. Inhibits HIV replication in peripheral blood monocytes that express CCR5.

All locus annotations are based on the sentinel SNP (rs3213636).
Download the detailed results of SNiPA's block annotation (PDF)

Linked genes

Genes hit or close-by


Results from other genome-wide association studies

No associations available.