Target | cis/trans | Study | SNP | SNP location | Maj/min allele | MAF | N | βinv | seinv | Pinv | fclog | Plog | Praw |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TAFI | cis | Discovery | rs9534288 | 13:46,605,441 | C/T | 0.28 | 979 | -0.596 | 0.047 | 1.1×10-33 | -1.080 | 2×10-31 | 9.9×10-32 |
TAFI | cis | Replication | rs2296642 | 13:46,656,669 | G/A | 0.30 | 337 | -0.447 | 0.075 | 7×10-9 | -1.060 | 3.3×10-7 | 2.8×10-8 |
Target (abbrv.) | TAFI |
Target (full name) | Carboxypeptidase B2 |
Somalogic ID (Sequence ID) | SL004015 (3518-54_2) |
Entrez Gene Symbol | CPB2 |
UniProt ID | Q96IY4 |
UniProt Comment |
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Wiki Pathways |
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Reactome |
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All locus annotations are based on the sentinel SNP (rs9534288) and 69 proxy variant(s) that is/are in linkage disequilibrium r2 ≥ 0.8. Linkage disequilibrium is based on data from the 1000 Genomes Project, phase 3 version 5, European population and was retrieved using SNiPA's Block Annotation feature.
Download the detailed results of SNiPA's block annotation (PDF)
Genes hit or close-by | |
Potentially regulated genes | |
eQTL genes |
Trait | P | Study | Source |
---|---|---|---|
cg09598590 (chr13:46563728) | 6.2×10-5 | 10.1101/033084 (DOI) | BIOS QTL cis-meQTLs |