Target | cis/trans | Study | SNP | SNP location | Maj/min allele | MAF | N | βinv | seinv | Pinv | fclog | Plog | Praw |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PPAC | cis | Discovery | rs300756 | 2:233,416 | G/A | 0.17 | 995 | -0.520 | 0.057 | 3×10-19 | -1.460 | 9.1×10-21 | 7×10-19 |
PPAC | cis | Replication | rs300705 | 2:240,785 | G/A | 0.34 | 337 | -0.461 | 0.066 | 1.7×10-11 | -1.510 | 2.8×10-11 | 1.3×10-8 |
Target (abbrv.) | PPAC |
Target (full name) | Low molecular weight phosphotyrosine protein phosphatase |
Somalogic ID (Sequence ID) | SL008063 (3858-5_1) |
Entrez Gene Symbol | ACP1 |
UniProt ID | P24666 |
UniProt Comment |
|
Pathway Interaction Database |
|
All locus annotations are based on the sentinel SNP (rs300756) and 1 proxy variant(s) that is/are in linkage disequilibrium r2 ≥ 0.8. Linkage disequilibrium is based on data from the 1000 Genomes Project, phase 3 version 5, European population and was retrieved using SNiPA's Block Annotation feature.
Download the detailed results of SNiPA's block annotation (PDF)
Genes hit or close-by | |
eQTL genes |
|
Trait | P | Study | Source |
---|---|---|---|
Cystatin C in serum | 2.6×10-4 | 20383146 (PMID) | GRASP2 nonQTL |