Locus 211

Top associations per target

Target	cis/trans	Study	SNP	SNP location	Maj/min allele	MAF	N	β_inv	se_inv	P_inv	fc_log	P_log	P_raw
CYTN	cis	Discovery	rs2070856	20:23,731,412	G/A	0.13	997	-0.555	0.061	5.6×10^-19	-1.290	9.5×10^-17	0.548
CYTN	cis	Replication	rs2070856	20:23,731,412	G/A	0.19	337	-0.259	0.092	0.005	-1.100	0.047	0.681

	inverse-normalized probe levels	log₂ transformed probe levels	raw probe levels
Discovery study
Replication study

Target (abbrv.)	CYTN
Target (full name)	Cystatin-SN
Somalogic ID (Sequence ID)	SL010456 (5459-33_3)
Entrez Gene Symbol	CST1
UniProt ID	P01037
UniProt Comment	Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Cystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well.

All locus annotations are based on the sentinel SNP (rs2070856).
Download the detailed results of SNiPA's block annotation (PDF)

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Genes hit or close-by	CST1 cystatin SN
eQTL genes	CST1 cystatin SN

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No associations available.