HelmholtzZentrum munich
WCMC

Connecting genetic risk to disease endpoints through the human blood plasma proteome

ONLINE SUPPLEMENTARY INFORMATION

Ideogram
Proteome annotation
Target annotations

Target: Calpain I

Target (abbrv.) Calpain I
Target (full name) Calpain I
Somalogic ID (Sequence ID) SL000337 (2668-70_2)
Entrez Gene Symbol CAPN1CAPNS1
UniProt ID P07384P04632
UniProt Comment
  • P07384: Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
  • P04632: Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
Wiki Pathways
  • Alzheimers Disease
  • Focal Adhesion
  • Integrin-mediated cell adhesion
Pathway Interaction Database
  • Signaling events mediated by PTP1B
Reactome
  • Degradation of the extracellular matrix
Pathway Studio
  • Focal Junction Assembly
pGWAS Locus 215
pGWAS NetworkGo to network view