HelmholtzZentrum munich
WCMC

Connecting genetic risk to disease endpoints through the human blood plasma proteome

ONLINE SUPPLEMENTARY INFORMATION

Ideogram
Proteome annotation
Target annotations

Target: Amphiregulin (AREG)

Target (abbrv.) AREG
Target (full name) Amphiregulin
Somalogic ID (Sequence ID) SL000136 (2970-60_2)
Entrez Gene Symbol AREG
UniProt ID P15514
UniProt Comment
  • Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.
Biomarker applications (based on IPA annotation)
  • diagnosis
  • efficacy
  • prognosis
  • response to therapy
Wiki Pathways
  • ErbB signaling pathway
  • FSH signaling pathway
Pathway Interaction Database
  • ErbB receptor signaling network
pGWAS Locus -
pGWAS NetworkGo to network view