HelmholtzZentrum munich
WCMC

Connecting genetic risk to disease endpoints through the human blood plasma proteome

ONLINE SUPPLEMENTARY INFORMATION

Ideogram
Proteome annotation
Target annotations

Target: Programmed cell death 1 ligand 2 (PD-L2)

Target (abbrv.) PD-L2
Target (full name) Programmed cell death 1 ligand 2
Somalogic ID (Sequence ID) SL004862 (3004-67_2)
Entrez Gene Symbol PDCD1LG2
UniProt ID Q9BQ51
UniProt Comment
  • Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).
Reactome
  • PD-1 signaling
Pathway Studio
  • Peripheral T-cell Tolerance Overview
pGWAS Locus 152
pGWAS NetworkGo to network view