HelmholtzZentrum munich
WCMC

Connecting genetic risk to disease endpoints through the human blood plasma proteome

ONLINE SUPPLEMENTARY INFORMATION

Ideogram
Proteome annotation
Target annotations

Target: Low affinity immunoglobulin epsilon Fc receptor (CD23)

Target (abbrv.) CD23
Target (full name) Low affinity immunoglobulin epsilon Fc receptor
Somalogic ID (Sequence ID) SL002706 (3291-30_2)
Entrez Gene Symbol FCER2
UniProt ID P06734
UniProt Comment
  • Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
Biomarker applications (based on IPA annotation)
  • diagnosis
Pathway Interaction Database
  • IL4-mediated signaling events
Reactome
  • NOTCH2 intracellular domain regulates transcription
pGWAS Locus 310
pGWAS NetworkGo to network view