HelmholtzZentrum munich
WCMC

Connecting genetic risk to disease endpoints through the human blood plasma proteome

ONLINE SUPPLEMENTARY INFORMATION

Ideogram
Proteome annotation
Target annotations

Target: Alanine aminotransferase 1 (ALT)

Target (abbrv.) ALT
Target (full name) Alanine aminotransferase 1
Somalogic ID (Sequence ID) SL000617 (3709-4_2)
Entrez Gene Symbol GPT
UniProt ID P24298
UniProt Comment
  • Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles (By similarity).
Wiki Pathways
  • Alanine and aspartate metabolism
UniPathway
  • L-alanine degradation via transaminase pathway
Reactome
  • Amino acid synthesis and interconversion (transamination)
pGWAS Locus -
pGWAS NetworkGo to network view