HelmholtzZentrum munich
WCMC

Connecting genetic risk to disease endpoints through the human blood plasma proteome

ONLINE SUPPLEMENTARY INFORMATION

Ideogram
Proteome annotation
Target annotations

Target: Plexin-C1 (PLXC1)

Target (abbrv.) PLXC1
Target (full name) Plexin-C1
Somalogic ID (Sequence ID) SL006406 (4564-2_2)
Entrez Gene Symbol PLXNC1
UniProt ID O60486
UniProt Comment
  • Receptor for SEMA7A, for smallpox semaphorin A39R, vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8 (By similarity).
Reactome
  • Other semaphorin interactions
pGWAS Locus 148, 261
pGWAS NetworkGo to network view