HelmholtzZentrum munich
WCMC

Connecting genetic risk to disease endpoints through the human blood plasma proteome

ONLINE SUPPLEMENTARY INFORMATION

Ideogram
Proteome annotation
Target annotations

Target: Estradiol 17-beta-dehydrogenase 1 (17-beta-HSD 1)

Target (abbrv.) 17-beta-HSD 1
Target (full name) Estradiol 17-beta-dehydrogenase 1
Somalogic ID (Sequence ID) SL004253 (4708-3_2)
Entrez Gene Symbol HSD17B1
UniProt ID P14061
UniProt Comment
  • Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH.
Biomarker applications (based on IPA annotation)
  • diagnosis
  • unspecified application
Wiki Pathways
  • Steroid Biosynthesis
UniPathway
  • estrogen biosynthesis
Reactome
  • Estrogen biosynthesis
  • The canonical retinoid cycle in rods (twilight vision)
pGWAS Locus -
pGWAS NetworkGo to network view