HelmholtzZentrum munich
WCMC

Connecting genetic risk to disease endpoints through the human blood plasma proteome

ONLINE SUPPLEMENTARY INFORMATION

Ideogram
Proteome annotation
Target annotations

Target: Glutathione S-transferase P (Glutathione S-transferase Pi)

Target (abbrv.) Glutathione S-transferase Pi
Target (full name) Glutathione S-transferase P
Somalogic ID (Sequence ID) SL003643 (4911-49_2)
Entrez Gene Symbol GSTP1
UniProt ID P09211
UniProt Comment
  • Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.
Biomarker applications (based on IPA annotation)
  • diagnosis
  • efficacy
  • prognosis
  • safety
  • unspecified application
Wiki Pathways
  • Arachidonate Epoxygenase / Epoxide Hydrolase
  • Diurnally regulated genes with circadian orthologs
  • metapathway biotransformation
Reactome
  • Detoxification of Reactive Oxygen Species
  • Glutathione conjugation
pGWAS Locus -
pGWAS NetworkGo to network view