HelmholtzZentrum munich
WCMC

Connecting genetic risk to disease endpoints through the human blood plasma proteome

ONLINE SUPPLEMENTARY INFORMATION

Ideogram
Proteome annotation
Target annotations

Target: Zona pellucida sperm-binding protein 4 (ZP4)

Target (abbrv.) ZP4
Target (full name) Zona pellucida sperm-binding protein 4
Somalogic ID (Sequence ID) N/A (7766-25_3)
Entrez Gene Symbol ZP4
UniProt ID Q12836
UniProt Comment
  • The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor.
pGWAS Locus -